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Literature summary for 2.7.8.B10 extracted from
- Discovery of a cardiolipin synthase utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates (2012), Proc. Natl. Acad. Sci. USA, 109, 16504-16509.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | P0A6H8 | cardiolipin synthase A | - |
| Escherichia coli | P0AA84 | cardiolipin synthase B | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| cardiolipin synthase A | - |
Escherichia coli |
| cardiolipin synthase B | - |
Escherichia coli |
| clsA | - |
Escherichia coli |
| clsB | - |
Escherichia coli |
| ybhO | - |
Escherichia coli |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | Escherichia coli has three cardiolipin synthases. Cardiolipin synthase A encoded by clsA, cardiolipin synthase B encoded by clsB and cardiolipin synthase C, encoded by clsC. Triple deletions of clsA, clsB, and clsC results in the complete depletion of cardiolipin synthase activity in Escherichia coli cells. The double mutant DELTAclsAB mutant still makes cardiolipin in the stationary phase | Escherichia coli |
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Release 2023.1 (January 2023)
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