BRENDA - Enzyme Database
show all sequences of 2.7.8.B10

The effects of phosphoglycerides on Escherichia coli cardiolipin synthase

Ragolia, L.; Tropp, B.E.; Biochim. Biophys. Acta 1214, 323-332 (1994)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
cardiolipin
phosphatidylethanolamine partially offsets inhibition by cardiolipin
Escherichia coli
additional information
not inhibited by phosphatidylinositol and bis-phosphatidate
Escherichia coli
phosphatidate
MgCl2 partially offsets inhibition by phosphatidate
Escherichia coli
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
46000
-
x * 46000, SDS-PAGE
Escherichia coli
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Escherichia coli
-
-
-
Purification (Commentary)
Commentary
Organism
-
Escherichia coli
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
a phosphatidylglycerol + a phosphatidylglycerol
-
727058
Escherichia coli
a cardiolipin + glycerol
-
-
-
?
Subunits
Subunits
Commentary
Organism
?
x * 46000, SDS-PAGE
Escherichia coli
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
cardiolipin
phosphatidylethanolamine partially offsets inhibition by cardiolipin
Escherichia coli
additional information
not inhibited by phosphatidylinositol and bis-phosphatidate
Escherichia coli
phosphatidate
MgCl2 partially offsets inhibition by phosphatidate
Escherichia coli
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
46000
-
x * 46000, SDS-PAGE
Escherichia coli
Purification (Commentary) (protein specific)
Commentary
Organism
-
Escherichia coli
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
a phosphatidylglycerol + a phosphatidylglycerol
-
727058
Escherichia coli
a cardiolipin + glycerol
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 46000, SDS-PAGE
Escherichia coli
Other publictions for EC 2.7.8.B10
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
739118
Noguchi
Complex evolution of two types ...
Cafeteria sp., Cantina marsupialis, no activity in Cafeteria roenbergensis, no activity in Developayella elegans, Wobblia lunata, Wobblia lunata NIES1015
Mol. Phylogenet. Evol.
101
133-141
2016
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6
6
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739625
Kusaka
Septal localization by membran ...
Bacillus subtilis 168, Bacillus subtilis
Res. Microbiol.
167
202-214
2016
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1
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738526
Buskirk
Moraxella catarrhalis expresse ...
Moraxella catarrhalis
J. Bacteriol.
196
107-120
2014
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3
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738626
Liu
Cardiolipin is dispensable for ...
Bacillus pseudofirmus, Bacillus pseudofirmus OF4
J. Biol. Chem.
289
2960-2971
2014
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3
3
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738264
Ohniwa
Alternative cardiolipin syntha ...
Staphylococcus aureus, Staphylococcus aureus N315
FEMS Microbiol. Lett.
338
141-146
2013
1
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1
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4
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3
6
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726689
Davlieva
Biochemical characterization o ...
Enterococcus faecalis, Enterococcus faecalis S613, Enterococcus faecium, Enterococcus faecium S447, Enterococcus faecium S613
Antimicrob. Agents Chemother.
57
289-296
2012
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2
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3
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1
8
2
1
1
5
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10
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3
2
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2
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3
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3
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728679
Tan
Discovery of a cardiolipin syn ...
Escherichia coli
Proc. Natl. Acad. Sci. USA
109
16504-16509
2012
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1
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727065
Quigley
E. coli cardiolipin synthase: ...
Escherichia coli
Biochim. Biophys. Acta
1788
2107-2113
2009
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3
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727063
Guo
A second Escherichia coli prot ...
Escherichia coli
Biochim. Biophys. Acta
1483
263-274
2000
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727058
Ragolia
The effects of phosphoglycerid ...
Escherichia coli
Biochim. Biophys. Acta
1214
323-332
1994
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3
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2
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727789
Hiraoka
Amplification and substantial ...
Escherichia coli
J. Biochem.
110
443-449
1991
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727710
Burritt
Properties of a membrane-bound ...
Lactobacillus plantarum, Lactobacillus plantarum ATCC 8014
J. Bacteriol.
123
972-977
1975
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728702
Hirschberg
Mechanism of the enzymatic syn ...
Escherichia coli
Proc. Natl. Acad. Sci. USA
69
648-651
1972
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