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Literature summary for 2.7.8.5 extracted from
- Purification and characterization of phosphatidylglycerolphosphate synthase from Schizosaccharomyces pombe (1998), J. Biol. Chem., 273, 4681-4688.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| cardiolipin | - |
Schizosaccharomyces pombe |  |
| Mg2+ | slight stimulation | Schizosaccharomyces pombe | |
| Triton X-100 | slight stimulation at 0.6 mM, inhibitory above | Schizosaccharomyces pombe | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Mn2+ | - |
Schizosaccharomyces pombe | |
| Triton X-100 | slight stimulation at 0.6 mM, inhibitory above | Schizosaccharomyces pombe | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | inner membrane | Schizosaccharomyces pombe | 5739 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | slight stimulation | Schizosaccharomyces pombe | |
| Mn2+ | inhibitory | Schizosaccharomyces pombe | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 60000 | - |
2 * 60000, SDS-PAGE | Schizosaccharomyces pombe |
| 120000 | - |
gel filtration | Schizosaccharomyces pombe |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Schizosaccharomyces pombe | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Schizosaccharomyces pombe |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 1.17 | - |
30°C, pH 7.5 | Schizosaccharomyces pombe |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDP-diacylglycerol + sn-glycero-3-phosphate | - |
Schizosaccharomyces pombe | CMP + phosphatidylglycerophosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 60000, SDS-PAGE | Schizosaccharomyces pombe |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
- |
Schizosaccharomyces pombe |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
- |
Schizosaccharomyces pombe |
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Release 2023.1 (January 2023)
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