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Literature summary for 2.7.8.46 extracted from

  • Brown, S.; Meredith, T.; Swoboda, J.; Walker, S.
    Staphylococcus aureus and Bacillus subtilis W23 make polyribitol wall teichoic acids using different enzymatic pathways (2010), Chem. Biol., 17, 1101-1110.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CDP-ribitol + 4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol Bacillus spizizenii
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 CMP + 4-O-[1-D-ribitylphospho-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
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 ?
CDP-ribitol + 4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol Bacillus spizizenii ATCC 23059
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 CMP + 4-O-[1-D-ribitylphospho-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
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 ?
additional information Bacillus spizizenii TarK functions to prime the wall teichoic acid intermediate for chain extension by TarL. TarK is only able to accept lipid-diphospho-GlcNAc-ManNAc-GroP, the TagB product, as a substrate ?
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 ?
additional information Bacillus spizizenii ATCC 23059 TarK functions to prime the wall teichoic acid intermediate for chain extension by TarL. TarK is only able to accept lipid-diphospho-GlcNAc-ManNAc-GroP, the TagB product, as a substrate ?
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 ?

Organism

Organism UniProt Comment Textmining
Bacillus spizizenii Q8RKJ1
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Bacillus spizizenii ATCC 23059 Q8RKJ1
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CDP-ribitol + 4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
-
 Bacillus spizizenii CMP + 4-O-[1-D-ribitylphospho-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
-
 ?
CDP-ribitol + 4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
-
 Bacillus spizizenii ATCC 23059 CMP + 4-O-[1-D-ribitylphospho-(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
-
 ?
additional information TarK functions to prime the wall teichoic acid intermediate for chain extension by TarL. TarK is only able to accept lipid-diphospho-GlcNAc-ManNAc-GroP, the TagB product, as a substrate Bacillus spizizenii ?
-
 ?
additional information TarK functions to prime the wall teichoic acid intermediate for chain extension by TarL. TarK is only able to accept lipid-diphospho-GlcNAc-ManNAc-GroP, the TagB product, as a substrate Bacillus spizizenii ATCC 23059 ?
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 ?

Synonyms

Synonyms Comment Organism
tarK
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 Bacillus spizizenii