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Literature summary for 2.7.8.45 extracted from

  • Brown, S.; Zhang, Y.; Walker, S.
    a revised pathway proposed for Staphylococcus aureus wall teichoic acid biosynthesis based on in vitro reconstitution of the intracellular steps (2008), Chem. Biol., 15, 12-21.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.8.45

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Staphylococcus aureus

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus Q2G1C1
-
-
Staphylococcus aureus NCTC 8325 Q2G1C1
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CDP-glycerol + 4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
-
 Staphylococcus aureus CDP + 4-O-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol enzyme TarF adds one unit of glycerol-3-phosphate to 4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol to produce (glycerol-3-phosphate)2-ManNAc-beta-(1,4)-GlcNAc-diphospho-lipid ?
CDP-glycerol + 4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
-
 Staphylococcus aureus NCTC 8325 CDP + 4-O-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol enzyme TarF adds one unit of glycerol-3-phosphate to 4-O-[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol to produce (glycerol-3-phosphate)2-ManNAc-beta-(1,4)-GlcNAc-diphospho-lipid ?

Synonyms

Synonyms Comment Organism
SAOUHSC_00223
-
 Staphylococcus aureus
tarF
-
 Staphylococcus aureus

General Information

General Information Comment Organism
physiological function gene products TarA, TarB, TarF, and TarL are required to convert the GlcNAc-diphosphate-lipid product of TarO to the full-length polyribitol polymer Staphylococcus aureus