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Literature summary for 2.7.8.41 extracted from

  • Gottier, P.; Serricchio, M.; Vitale, R.; Corcelli, A.; Buetikofer, P.
    Cross-species complementation of bacterial- and eukaryotic-type cardiolipin synthases (2017), Microb. Cell, 4, 376-383 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.8.41

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Saccharomyces cerevisiae 5739
-
mitochondrion
-
 Trypanosoma brucei 5739
-

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-
Trypanosoma brucei
-
-
-

Synonyms

Synonyms Comment Organism
CLS
-
 Trypanosoma brucei
CRD1
-
 Saccharomyces cerevisiae

General Information

General Information Comment Organism
physiological function expression of CLS complements cardiolipin production in CRD1 knockout Saccharomyces cerevisiae and partly restores wild-type colony forming capability under stress conditions. Cardiolipin remodeling appears to be impaired in the transgenic construct. No complementation is observed by heterologous expression of Saccharomyces cerevisiae Crd1 in conditional CLS knockout trypanosomes, despite proper mitochondrial targeting of the protein Trypanosoma brucei
physiological function expression of Trypanosoma brucei CLS complements cardiolipin production in CRD1 knockout Saccharomyces cerevisiae and partly restores wild-type colony forming capability under stress conditions. Cardiolipin remodeling appears to be impaired in the transgenic construct. No complementation is observed by heterologous expression of Crd1 in conditional CLS knockout trypanosomes, despite proper mitochondrial targeting of the protein Saccharomyces cerevisiae