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Literature summary for 2.7.8.40 extracted from

  • Merino, S.; Jimenez, N.; Molero, R.; Bouamama, L.; Regué, M.; Tomas, J.M.
    A UDP-HexNAc:polyprenol-P GalNAc-1-P transferase (WecP) representing a new subgroup of the enzyme family (2011), J. Bacteriol., 193, 1943-1952.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.8.40

Cloned(Commentary)

Cloned (Comment) Organism
His6-WecP is overproduced in Escherichia coli BL21(lambdaD3) Aeromonas hydrophila

Protein Variants

Protein Variants Comment Organism
additional information AH-3DELTAwecP mutant is completely unable to biosynthesize the O34-antigen lipopolysaccharide Aeromonas hydrophila

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Aeromonas hydrophila 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate Aeromonas hydrophila
-
 UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
-
 ?
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate Aeromonas hydrophila AH-3
-
 UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
-
 ?

Organism

Organism UniProt Comment Textmining
Aeromonas hydrophila
-
-
-
Aeromonas hydrophila AH-3
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Aeromonas hydrophila

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate
-
 Aeromonas hydrophila UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
-
 ?
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate no activity with UDP-N-acetyl-D-glucosamine Aeromonas hydrophila UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
-
 ?
UDP-N-acetyl-alpha-D-galactosamine + ditrans,octacis-undecaprenyl phosphate
-
 Aeromonas hydrophila AH-3 UMP + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
-
 ?

Synonyms

Synonyms Comment Organism
UDP-GalNAc:polyprenol-P GalNAc-1-P transferase
-
 Aeromonas hydrophila
WecP
-
 Aeromonas hydrophila

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Aeromonas hydrophila

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
 assay at Aeromonas hydrophila

General Information

General Information Comment Organism
malfunction AH-3DELTAwecP mutant is completely unable to biosynthesize the O34-antigen lipopolysaccharide Aeromonas hydrophila