Literature summary for 2.7.8.33 extracted from

Rush, J.S.; Rick, P.D.; Waechter, C.J.
Polyisoprenyl phosphate specificity of UDP-GlcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transferase from E.coli (1997), Glycobiology, 7, 315-322.

Search for more literature for 2.7.8.33

Inhibitors

Inhibitors	Comment	Organism	Structure
CHAPS	i.e 3-[(3-cholamidopropyl)-dimethylammonio]-lpropane-sulfonate	Escherichia coli

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0056	-	UDP-N-acetyl-D-glucosamine	pH 8.0, 37°C	Escherichia coli

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Escherichia coli	16020	-

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	maximal in presence of 20-40 mM MgCl2	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	P0AC78	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDP-N-acetyl-D-glucosamine + ditrans,polycis-undecaprenyl phosphate	the enzyme has a strict preference for fully unsaturated polyprenyl phosphate substrates. Undecaprenyl phosphate and pentadecaprenyl phosphate are utilized with higher catalytic efficiency compared to nonaprenyl phosphate	Escherichia coli	UMP + N-acetyl-D-glucosaminyldiphospho-ditrans,polycis-undecaprenol	-	?
UDP-N-acetyl-D-glucosamine + nonaprenyl phosphate	the enzyme has a strict preference for fully unsaturated polyprenyl phosphate substrates. Undecaprenyl phosphate and pentadecaprenyl phosphate are utilized with higher catalytic efficiency compared to nonaprenyl phosphate	Escherichia coli	UMP + N-acetyl-D-glucosaminyldiphospho-nonaprenol	-	?
UDP-N-acetyl-D-glucosamine + pentadecaprenyl phosphate	the enzyme has a strict preference for fully unsaturated polyprenyl phosphate substrates. Undecaprenyl phosphate and pentadecaprenyl phosphate are utilized with higher catalytic efficiency compared to nonaprenyl phosphate	Escherichia coli	UMP + N-acetyl-D-glucosaminyldiphospho-pentadecaprenol	-	?

Synonyms

Synonyms	Comment	Organism
GlcNAc-P-P-Und synthase	-	Escherichia coli
GPT	-	Escherichia coli
UDP-GlcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transferase	-	Escherichia coli

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Release 2023.1 (January 2023)