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Literature summary for 2.7.8.27 extracted from
- SMS overexpression and knockdown: Impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis (2008), J. Lipid Res., 49, 376-385.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Chinese hamster ovary cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ceramide + phosphatidylcholine | - |
Homo sapiens | sphingomyelin + 1,2-diacyl-sn-glycerol | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SMS1 | isoform | Homo sapiens |
| SMS2 | isoform | Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | isoforms SMS1 and SMS2 are key factors in the control of sphingomyelin and 1,2-diacyl-sn-glycerol levels within the cell and thus influence apoptosis | Homo sapiens |
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Release 2023.1 (January 2023)
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