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Literature summary for 2.7.8.26 extracted from

  • Zayas, C.L.; Escalante-Semerena, J.C.
    Reassessment of the late steps of coenzyme B12 synthesis in Salmonella enterica: evidence that dephosphorylation of adenosylcobalamin-5-phosphate by the CobC phosphatase is the last step of the pathway (2007), J. Bacteriol., 189, 2210-2218.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli strain C41(DE3) Salmonella enterica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
adenosylcobinamide-GDP + alpha-ribazole-5'-phosphate + H2O Salmonella enterica
-
GMP + adenosylcobalamin + phosphate + H+
-
?

Organism

Organism UniProt Comment Textmining
Salmonella enterica
-
serovar typhimurium
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
adenosylcobinamide-GDP + alpha-ribazole
-
Salmonella enterica GMP + adenosylcobalamin
-
?
adenosylcobinamide-GDP + alpha-ribazole 5'-phosphate alpha-ribazole-5’-phosphate is a more preferred substrate compared to alpha-ribazole Salmonella enterica GMP + adenosylcobalamin 5'-phosphate
-
?
adenosylcobinamide-GDP + alpha-ribazole-5'-phosphate + H2O
-
Salmonella enterica GMP + adenosylcobalamin + phosphate + H+
-
?

Synonyms

Synonyms Comment Organism
adenosylcobalamin-5’-phosphate synthase
-
Salmonella enterica
AdoCbl-5’-P synthase
-
Salmonella enterica
CobS
-
Salmonella enterica