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Literature summary for 2.7.8.2 extracted from

  • Kanoh, H.; Ohno, K.
    Solubilization and purification of rat liver microsomal 1,2-diacylglycerol: CDP-choline cholinephosphotransferase and 1,2-diacylglycerol: CDP-ethanolamine ethanolaminephosphotransferase (1976), Eur. J. Biochem., 66, 201-210.
    View publication on PubMed
Search for more literature for 2.7.8.2

Activating Compound

Activating Compound Comment Organism Structure
deoxycholate stimulates Rattus norvegicus
Phospholipids microsomal phospholipids required for maximal activity Rattus norvegicus

Application

Application Comment Organism
medicine exposure of cortical neurons to neurotoxic concentrations of N-methyl-D-aspartate strongly reduces enzymic activity Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
CDPethanolamine
-
 Rattus norvegicus
Triton X-100 X-100 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Rattus norvegicus
Mg2+ enzyme separated into Mg2+-requiring and Mn2+-requiring components Rattus norvegicus
Mn2+ enzyme separated into Mg2+-requiring and Mn2+-requiring components Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CDP-choline + 1,2-diacylglycerol
-
 Rattus norvegicus CMP + a phosphatidylcholine
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8 8.5
-
 Rattus norvegicus