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Literature summary for 2.7.8.2 extracted from

  • Ishidate, K.; Matsuo, R.; Nakazawa, Y.
    CDPcholine:1,2-diacylglycerol cholinephosphotransferase from rat liver microsomes. I. Solubilization and characterization of the partially purified enzyme and the possible existence of an endogenous inhibitor (1993), Lipids, 28, 89-96.
    View publication on PubMed
Search for more literature for 2.7.8.2

Inhibitors

Inhibitors Comment Organism Structure
CHAPS irreversible inactivation at the solubilization step Rattus norvegicus
additional information heat-labile, nondialyzable endogenous inhibitor may act at the binding step of the enzyme to its lipid substrate Rattus norvegicus
n-octylglucoside irreversible inactivation at the solubilization step Rattus norvegicus
Triton X-100 irreversible inactivation at the solubilization step; X-100 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ requires Mg2+ rather than Mn2+, particularly at physiological concentrations less than 5 mM Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.13
-
 37°C, pH 8.5 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CDP-choline + 1,2-diacylglycerol
-
 Rattus norvegicus CMP + a phosphatidylcholine
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Rattus norvegicus