Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of GlcNAc-1-phosphotransferase-defective mice and enzyme-defective mouse embryonic fibroblasts | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
Golgi apparatus | - |
Mus musculus | 5794 | - |
Golgi apparatus | - |
Homo sapiens | 5794 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the lysosomal integral membrane protein type 2 (LIMP-2/SCARB2) is a mannose 6-phosphate-independent trafficking receptor for beta-glucocerebrosidase and no substrate of the enzyme, M6P-independent lysosomal sorting of LIMP-2, overview. beta-Glucocerebrosidase is also no substrate for the enzyme | ? | - |
? | |
UDP-N-acetyl-D-glucosamine + lysosomal-cathepsin Z D-mannose | Homo sapiens | - |
UMP + lysosomal-cathepsin Z N-acetyl-D-glucosaminyl-phospho-D-mannose | - |
? | |
UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose | Mus musculus | - |
UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose | - |
? | |
UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose | Homo sapiens | - |
UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q3T906 AND Q9UJJ9 | alpha/beta-, and gamma-subunit encoding genes | - |
Mus musculus | Q69ZN6 AND Q6S5C2 | alpha/beta-, and gamma-subunit encoding genes | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | an N-linked glycoprotein | Mus musculus |
glycoprotein | an N-linked glycoprotein | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
additional information | no activity in fibroblasts | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the lysosomal integral membrane protein type 2 (LIMP-2/SCARB2) is a mannose 6-phosphate-independent trafficking receptor for beta-glucocerebrosidase and no substrate of the enzyme, M6P-independent lysosomal sorting of LIMP-2, overview. beta-Glucocerebrosidase is also no substrate for the enzyme | Homo sapiens | ? | - |
? | |
UDP-N-acetyl-D-glucosamine + lysosomal-cathepsin Z D-mannose | - |
Homo sapiens | UMP + lysosomal-cathepsin Z N-acetyl-D-glucosaminyl-phospho-D-mannose | - |
? | |
UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose | - |
Mus musculus | UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose | - |
? | |
UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose | - |
Homo sapiens | UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GlcNAc-1-phosphotransferase | - |
Mus musculus |
GlcNAc-1-phosphotransferase | - |
Homo sapiens |
GlcNAc-1PT | - |
Mus musculus |
GlcNAc-1PT | - |
Homo sapiens |
M6P-forming GlcNAc-1-phosphotransferase | - |
Mus musculus |
M6P-forming GlcNAc-1-phosphotransferase | - |
Homo sapiens |
M6P-forming N-acetylglucosamine-1-phosphotransferase | - |
Mus musculus |
M6P-forming N-acetylglucosamine-1-phosphotransferase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
additional information | the lysosomal integral membrane protein type 2 (LIMP-2/SCARB2) is a mannose 6-phosphate-independent trafficking receptor for beta-glucocerebrosidase and no substrate of the enzyme, M6P-independent lysosomal sorting of LIMP-2, overview | Homo sapiens |