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Literature summary for 2.7.8.17 extracted from
- UDP-GlcNAc:Glycoprotein N-acetylglucosamine-1-phosphotransferase mediates the initial step in the formation of the methylphosphomannosyl residues on the high mannose oligosaccharides of Dictyostelium discoideum glycoproteins (2010), Biochem. Biophys. Res. Commun., 393, 678-681.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Dictyostelium discoideum | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-N-acetyl-D-glucosamine + methyl alpha-D-mannopyranoside | - |
Dictyostelium discoideum | UMP + methyl (6-O-alpha-N-acetyl-D-glucosaminylphospho)-alpha-D-mannopyranoside | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| gpt1 | - |
Dictyostelium discoideum |
| UDP-GlcNAc:glycoprotein N-acetylglucosamine-1-phosphotransferase | - |
Dictyostelium discoideum |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Dictyostelium discoideum |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Dictyostelium discoideum |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | extracts of two mutant cell lines transfer UDP-N-acetyl-D-glucosamine from N-acetyl-D-glucosamine to mannose residues at less than 5% the wild type value. In addition, the lysosomal hydrolases of these mutant clones fail to bind to a cation-independent mannose 6-phosphate receptor affinity column | Dictyostelium discoideum |
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Release 2023.1 (January 2023)
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