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Literature summary for 2.7.8.11 extracted from

  • Monaco, M.E.; Feldman, M.; Kleinberg, D.L.
    Identification of rat liver phosphatidylinositol synthase as a 21 kDa protein (1994), Biochem. J., 304, 301-305.
No PubMed abstract available
Search for more literature for 2.7.8.11

Activating Compound

Activating Compound Comment Organism Structure
Triton X-100 0.1% increases activity by 15fold Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
6-O-(N-heptyl-carbamoyl)methyl-alpha-D-glucopyranoside Hecameg, above 5 mM Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0095
-
 CDP-diacylglycerol pH 8.6, 37°C Rattus norvegicus
1.3
-
 myo-inositol pH 8.6, 37°C Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+
-
 Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
21000
-
 ? * 21000, SDS-PAGE Rattus norvegicus
150000 200000 gel filtration Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CDP-diacylglycerol + myo-inositol Rattus norvegicus
-
 CMP + phosphatidyl-1D-myo-inositol
-
 r

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 rat
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.788
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CDP-diacylglycerol + myo-inositol
-
 Rattus norvegicus CMP + phosphatidyl-1D-myo-inositol
-
 r

Subunits

Subunits Comment Organism
? ? * 21000, SDS-PAGE Rattus norvegicus