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Literature summary for 2.7.8.1 extracted from
- Plasmenylethanolamine synthesis in Leishmania major (2016), Mol. Microbiol., 101, 238-249 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Leishmania major | Q4QDW1 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| LMJF_18_0810 | - |
Leishmania major |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | ethanolamine phosphotransferase-null parasites are largely devoid of plasmenylethanolamine and fully viable in regular medium but fail to proliferate in the absence of fetal bovine serum. They exhibit significant abnormalities in the synthesis and localization of GPI-anchored surface molecules. Ethanolamine phosphotransferase-null mutants also show attenuated virulence in BALB/c mice | Leishmania major |
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