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Literature summary for 2.7.8.1 extracted from
- NMDA receptor overactivation inhibits phospholipid synthesis by decreasing choline-ethanolamine phosphotransferase activity (2003), J. Neurosci., 23, 4100-4107.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | exposure of cortical neurons to neurotoxic concentrations of N-methyl-D-aspartate strongly reduces enzymic activity | Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| N-Methyl-D-aspartate | strong | Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
fetus, dual-specificity enzyme, activity of EC 2.7.8.1 and EC 2.7.8.2 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | of fetus | Rattus norvegicus | - |
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Release 2023.1 (January 2023)
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