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Literature summary for 2.7.7.B16 extracted from

  • Wu, K.; Lai, X.; Guo, X.; Hu, J.; Xiang, X.; Huang, L.
    Interplay between primase and replication factor C in the hyperthermophilic archaeon Sulfolobus solfataricus (2006), Mol. Microbiol., 63, 826-837.
    View publication on PubMed
Search for more literature for 2.7.7.B16

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NTP + n NTP Saccharolobus solfataricus the small subunit of the clamp loader replication factor C (RFC) of Sulfolobus solfataricus interacts with both the catalytic and non-catalytic subunits of the primase. The primase-clamp loader replication factor C interaction modulates the activities of both enzymes and therefore may be involved in the regulation of primer synthesis and the transfer of primers to DNA polymerase in archaea N(pN)n + n diphosphate
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NTP + n NTP Saccharolobus solfataricus P2 the small subunit of the clamp loader replication factor C (RFC) of Sulfolobus solfataricus interacts with both the catalytic and non-catalytic subunits of the primase. The primase-clamp loader replication factor C interaction modulates the activities of both enzymes and therefore may be involved in the regulation of primer synthesis and the transfer of primers to DNA polymerase in archaea N(pN)n + n diphosphate
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 ?

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus Q9UWW1 and Q97Z83 Q9UWW1: large subunit, Q97Z83: small subunit
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Saccharolobus solfataricus P2 Q9UWW1 and Q97Z83 Q9UWW1: large subunit, Q97Z83: small subunit
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NTP + n NTP the small subunit of the clamp loader replication factor C (RFC) of Sulfolobus solfataricus interacts with both the catalytic and non-catalytic subunits of the primase. The primase-clamp loader replication factor C interaction modulates the activities of both enzymes and therefore may be involved in the regulation of primer synthesis and the transfer of primers to DNA polymerase in archaea Saccharolobus solfataricus N(pN)n + n diphosphate
-
 ?
NTP + n NTP the small subunit of the clamp loader replication factor C (RFC) of Sulfolobus solfataricus interacts with both the catalytic and non-catalytic subunits of the primase. The primase-clamp loader replication factor C interaction modulates the activities of both enzymes and therefore may be involved in the regulation of primer synthesis and the transfer of primers to DNA polymerase in archaea Saccharolobus solfataricus P2 N(pN)n + n diphosphate
-
 ?

Subunits

Subunits Comment Organism
heterodimer
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 Saccharolobus solfataricus