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Literature summary for 2.7.7.97 extracted from
- The initiation of peptide formation in the biosynthesis of actinomycin (1993), J. Biol. Chem., 268, 10612-10620.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 3-hydroxy-4-methylanthranilate | Streptomyces anulatus | - |
diphosphate + 3-hydroxy-4-methylanthranilyl-adenylate | - |
? |  |
| ATP + 3-hydroxy-4-methylanthranilate | Streptomyces anulatus X2-18 | - |
diphosphate + 3-hydroxy-4-methylanthranilyl-adenylate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptomyces anulatus | - |
- |
- |
| Streptomyces anulatus X2-18 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| DEAE-cellulose column chromatography, and Superdex 200 gel filtration | Streptomyces anulatus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 3-hydroxy-4-methylanthranilate | - |
Streptomyces anulatus | diphosphate + 3-hydroxy-4-methylanthranilyl-adenylate | - |
? | |
| ATP + 3-hydroxy-4-methylanthranilate | - |
Streptomyces anulatus X2-18 | diphosphate + 3-hydroxy-4-methylanthranilyl-adenylate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ACMS I | - |
Streptomyces anulatus |
| actinomycin synthase I | - |
Streptomyces anulatus |
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Release 2023.1 (January 2023)
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