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Literature summary for 2.7.7.97 extracted from

  • Keller, U.
    Acyl pentapeptide lactone synthesis in actinomycin-producing Streptomycetes by feeding with structural analogs of 4-methyl-3-hydroxyanthranilic acid (1984), J. Biol. Chem., 259, 8226-8231.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 3-hydroxy-4-methylanthranilate Streptomyces antibioticus
-
diphosphate + 3-hydroxy-4-methylanthranilyl-adenylate
-
?
ATP + 3-hydroxy-4-methylanthranilate Streptomyces anulatus
-
diphosphate + 3-hydroxy-4-methylanthranilyl-adenylate
-
?
ATP + 3-hydroxy-4-methylanthranilate Streptomyces antibioticus ATCC 14888
-
diphosphate + 3-hydroxy-4-methylanthranilyl-adenylate
-
?
ATP + 3-hydroxy-4-methylanthranilate Streptomyces anulatus ATCC 11523
-
diphosphate + 3-hydroxy-4-methylanthranilyl-adenylate
-
?

Organism

Organism UniProt Comment Textmining
Streptomyces antibioticus
-
-
-
Streptomyces antibioticus ATCC 14888
-
-
-
Streptomyces anulatus
-
-
-
Streptomyces anulatus ATCC 11523
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 3-hydroxy-4-methylanthranilate
-
Streptomyces antibioticus diphosphate + 3-hydroxy-4-methylanthranilyl-adenylate
-
?
ATP + 3-hydroxy-4-methylanthranilate
-
Streptomyces anulatus diphosphate + 3-hydroxy-4-methylanthranilyl-adenylate
-
?
ATP + 3-hydroxy-4-methylanthranilate
-
Streptomyces antibioticus ATCC 14888 diphosphate + 3-hydroxy-4-methylanthranilyl-adenylate
-
?
ATP + 3-hydroxy-4-methylanthranilate
-
Streptomyces anulatus ATCC 11523 diphosphate + 3-hydroxy-4-methylanthranilyl-adenylate
-
?

Synonyms

Synonyms Comment Organism
4-MHA-activating enzyme
-
Streptomyces antibioticus
4-MHA-activating enzyme
-
Streptomyces anulatus