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Literature summary for 2.7.7.85 extracted from
- Inhibition of cyclic diadenylate cyclase, DisA, by polyphenols (2016), Sci. Rep., 6, 25445.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Tannic acid | inhibits both DisA and phosphodiesterase YybT | Bacillus subtilis |  |
| theaflavin-3'-gallate | specifically inhibits DisA but not phosphodiesterase YybT | Bacillus subtilis | |
| theaflavin-3,3'-digallate | specifically inhibits DisA but not phosphodiesterase YybT | Bacillus subtilis | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| disA | - |
Bacillus subtilis |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.0085 | - |
pH 7.5, 30°C | Bacillus subtilis | theaflavin-3,3'-digallate | |
| 0.0236 | - |
pH 7.5, 30°C | Bacillus subtilis | theaflavin-3'-gallate | |
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Release 2023.1 (January 2023)
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