Organism | UniProt | Comment | Textmining |
---|---|---|---|
Lactococcus lactis | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
CdaA | - |
Lactococcus lactis |
General Information | Comment | Organism |
---|---|---|
physiological function | the mutation I154F in phosphoglucosamine mutase gene GlmM results in a lowering of the cyclic di-AMP level and a reduction in the key peptidoglycan precursor UDP-N-acetylglucosamine. Cyclic di-AMP synthesis by CdaA is inhibited by GlmM mutant I154F more than GlmM and GlmM mutant I154F binds more strongly to CdaA than GlmM. Mutations in the cdaA restore osmoresistance in phosphodiesterase gdpP-defective mutants | Lactococcus lactis |