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Literature summary for 2.7.7.85 extracted from

  • Rismondo, J.; Gibhardt, J.; Rosenberg, J.; Kaever, V.; Halbedel, S.; Commichau, F.M.
    Phenotypes associated with the essential diadenylate cyclase CdaA and its potential regulator CdaR in the human pathogen Listeria monocytogenes (2016), J. Bacteriol., 198, 416-426.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane CdaA is an integral membrane protein that interacts with its potential regulatory protein, CdaR, via the transmembrane protein domain. The presence of the CdaR protein is not required for the membrane localization and abundance of CdaA Listeria monocytogenes 16020
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Organism

Organism UniProt Comment Textmining
Listeria monocytogenes Q8Y5E4
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Listeria monocytogenes ATCC BAA-679 Q8Y5E4
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Synonyms

Synonyms Comment Organism
CdaA
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Listeria monocytogenes
dacA
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Listeria monocytogenes

General Information

General Information Comment Organism
physiological function regulator protein CdaR negatively influences CdaA activity and the role of CdaR is most evident at a high growth temperature. A cdaR mutant strain is less susceptible to lysozyme. CdaA contributes to cell division, and cells depleted of CdaA are prone to lysis. The growth defect of a CdaA depletion strain can be partially restored by increasing the osmolarity of the growth medium Listeria monocytogenes