Cloned (Comment) | Organism |
---|---|
gene N308_13623, DNA and amino acid sequence determination and analysis, sequence comparisons of avian OASL enzymes, phylogenetic analysis, recombinant expression of EGFP-tagged enzyme in HEK-293FT and BHK-21 cells | Struthio camelus australis |
gene OAS-L, DNA and amino acid sequence determination and analysis, sequence comparisons of avian OASL enzymes, phylogenetic analysis, recombinant expression of EGFP-tagged enzyme in HEK-293FT and BHK-21 cells | Anas platyrhynchos |
gene OAS-L, DNA and amino acid sequence determination and analysis, sequence comparisons of avian OASL enzymes, phylogenetic analysis, recombinant expression of EGFP-tagged enzyme in HEK-293FT and BHK-21 cells | Anser cygnoides |
gene OASL, DNA and amino acid sequence determination and analysis, sequence comparisons of avian OASL enzymes, phylogenetic analysis, recombinant expression of EGFP-tagged enzyme in HEK-293FT and BHK-21 cells | Gallus gallus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Anas platyrhynchos | |
Mg2+ | required | Anser cygnoides | |
Mg2+ | required | Struthio camelus australis | |
Mg2+ | required | Gallus gallus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3 ATP | Anas platyrhynchos | - |
pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
3 ATP | Anser cygnoides | - |
pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
3 ATP | Struthio camelus australis | - |
pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
3 ATP | Gallus gallus | - |
pppA2'p5'A2'p5'A + 2 diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Anas platyrhynchos | A0A1B1V538 | - |
- |
Anser cygnoides | A0A1B1V537 | - |
- |
Gallus gallus | H9L0X6 | - |
- |
Struthio camelus australis | A0A093JNH5 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3 ATP | - |
Anas platyrhynchos | pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
3 ATP | - |
Anser cygnoides | pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
3 ATP | - |
Struthio camelus australis | pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
3 ATP | - |
Gallus gallus | pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
additional information | enzyme chOASL possesses the enzymatic activity to convert the ATP to 2'-5'-A up to tetramer | Gallus gallus | ? | - |
- |
|
additional information | enzyme duOASL possesses the enzymatic activity to convert the ATP to 2'-5'-A up to tetramer | Anas platyrhynchos | ? | - |
- |
|
additional information | enzyme goOASL possesses the enzymatic activity to convert the ATP to 2'-5'-A up to tetramer | Anser cygnoides | ? | - |
- |
|
additional information | enzyme osOASL possesses the enzymatic activity to convert the ATP to 2'-5'-A up to tetramer, very low activity | Struthio camelus australis | ? | - |
- |
Synonyms | Comment | Organism |
---|---|---|
2'-5'-oligoadenylate synthetase | - |
Anas platyrhynchos |
2'-5'-oligoadenylate synthetase | - |
Anser cygnoides |
2'-5'-oligoadenylate synthetase | - |
Struthio camelus australis |
2'-5'-oligoadenylate synthetase | - |
Gallus gallus |
chOASL | - |
Gallus gallus |
duOASL | - |
Anas platyrhynchos |
goOASL | - |
Anser cygnoides |
N308_13623 | - |
Struthio camelus australis |
OAS | - |
Anas platyrhynchos |
OAS | - |
Anser cygnoides |
OAS | - |
Struthio camelus australis |
OAS | - |
Gallus gallus |
OAS-L | - |
Anas platyrhynchos |
OAS-L | - |
Anser cygnoides |
OAS3 | - |
Struthio camelus australis |
OASL | - |
Gallus gallus |
osOAS1 | - |
Struthio camelus australis |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Anas platyrhynchos |
30 | - |
assay at | Anser cygnoides |
30 | - |
assay at | Struthio camelus australis |
30 | - |
assay at | Gallus gallus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Anas platyrhynchos |
7.4 | - |
assay at | Anser cygnoides |
7.4 | - |
assay at | Struthio camelus australis |
7.4 | - |
assay at | Gallus gallus |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme shows inhibitory activity on WNV replicon replication | Anas platyrhynchos |
physiological function | the enzyme shows inhibitory activity on WNV replicon replication | Anser cygnoides |
physiological function | the enzyme shows inhibitory activity on WNV replicon replication | Struthio camelus australis |
physiological function | the enzyme shows inhibitory activity on WNV replicon replication | Gallus gallus |