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Literature summary for 2.7.7.84 extracted from
- Functional analysis of duck, goose, and ostrich 2'-5'-oligoadenylate synthetase (2018), Infect. Genet. Evol., 62, 220-232 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene N308_13623, DNA and amino acid sequence determination and analysis, sequence comparisons of avian OASL enzymes, phylogenetic analysis, recombinant expression of EGFP-tagged enzyme in HEK-293FT and BHK-21 cells | Struthio camelus australis |
| gene OAS-L, DNA and amino acid sequence determination and analysis, sequence comparisons of avian OASL enzymes, phylogenetic analysis, recombinant expression of EGFP-tagged enzyme in HEK-293FT and BHK-21 cells | Anas platyrhynchos |
| gene OAS-L, DNA and amino acid sequence determination and analysis, sequence comparisons of avian OASL enzymes, phylogenetic analysis, recombinant expression of EGFP-tagged enzyme in HEK-293FT and BHK-21 cells | Anser cygnoides |
| gene OASL, DNA and amino acid sequence determination and analysis, sequence comparisons of avian OASL enzymes, phylogenetic analysis, recombinant expression of EGFP-tagged enzyme in HEK-293FT and BHK-21 cells | Gallus gallus |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required | Anas platyrhynchos |  |
| Mg2+ | required | Anser cygnoides | |
| Mg2+ | required | Struthio camelus australis | |
| Mg2+ | required | Gallus gallus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3 ATP | Anas platyrhynchos | - |
pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
| 3 ATP | Anser cygnoides | - |
pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
| 3 ATP | Struthio camelus australis | - |
pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
| 3 ATP | Gallus gallus | - |
pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Anas platyrhynchos | A0A1B1V538 | - |
- |
| Anser cygnoides | A0A1B1V537 | - |
- |
| Gallus gallus | H9L0X6 | - |
- |
| Struthio camelus australis | A0A093JNH5 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3 ATP | - |
Anas platyrhynchos | pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
| 3 ATP | - |
Anser cygnoides | pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
| 3 ATP | - |
Struthio camelus australis | pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
| 3 ATP | - |
Gallus gallus | pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
| additional information | enzyme chOASL possesses the enzymatic activity to convert the ATP to 2'-5'-A up to tetramer | Gallus gallus | ? | - |
- |
|
| additional information | enzyme duOASL possesses the enzymatic activity to convert the ATP to 2'-5'-A up to tetramer | Anas platyrhynchos | ? | - |
- |
|
| additional information | enzyme goOASL possesses the enzymatic activity to convert the ATP to 2'-5'-A up to tetramer | Anser cygnoides | ? | - |
- |
|
| additional information | enzyme osOASL possesses the enzymatic activity to convert the ATP to 2'-5'-A up to tetramer, very low activity | Struthio camelus australis | ? | - |
- |
|
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 2'-5'-oligoadenylate synthetase | - |
Anas platyrhynchos |
| 2'-5'-oligoadenylate synthetase | - |
Anser cygnoides |
| 2'-5'-oligoadenylate synthetase | - |
Struthio camelus australis |
| 2'-5'-oligoadenylate synthetase | - |
Gallus gallus |
| chOASL | - |
Gallus gallus |
| duOASL | - |
Anas platyrhynchos |
| goOASL | - |
Anser cygnoides |
| N308_13623 | - |
Struthio camelus australis |
| OAS | - |
Anas platyrhynchos |
| OAS | - |
Anser cygnoides |
| OAS | - |
Struthio camelus australis |
| OAS | - |
Gallus gallus |
| OAS-L | - |
Anas platyrhynchos |
| OAS-L | - |
Anser cygnoides |
| OAS3 | - |
Struthio camelus australis |
| OASL | - |
Gallus gallus |
| osOAS1 | - |
Struthio camelus australis |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Anas platyrhynchos |
| 30 | - |
assay at | Anser cygnoides |
| 30 | - |
assay at | Struthio camelus australis |
| 30 | - |
assay at | Gallus gallus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Anas platyrhynchos |
| 7.4 | - |
assay at | Anser cygnoides |
| 7.4 | - |
assay at | Struthio camelus australis |
| 7.4 | - |
assay at | Gallus gallus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme shows inhibitory activity on WNV replicon replication | Anas platyrhynchos |
| physiological function | the enzyme shows inhibitory activity on WNV replicon replication | Anser cygnoides |
| physiological function | the enzyme shows inhibitory activity on WNV replicon replication | Struthio camelus australis |
| physiological function | the enzyme shows inhibitory activity on WNV replicon replication | Gallus gallus |
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Release 2023.1 (January 2023)
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