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Literature summary for 2.7.7.84 extracted from

  • Bhosle, S.; Hunt, A.; Chaudhary, J.
    A modified coupled spectrophotometric method to detect 2-5 oligoadenylate synthetase activity in prostate cell lines (2016), Biol. Proced. Online, 18, 009.
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
analysis modified coupled spectrophotometric assay to detect 2-5 oligoadenylate synthetase enzyme activity in prostate cell lines as a model system. The phosphates generated by the OAS enzymatic reaction are coupled with conversion of the substrate 2-amino-6-mercapto-7-methylpurine ribonucleoside to a purine base product, 2-amino-6-mercapto-7-methylpurine and ribose1-phosphate via a purine nucleoside phosphorylase Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
DU-145 cell cell line displays high enzymatic activity Homo sapiens
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prostate cancer cell line
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 Homo sapiens
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RWPE-1 cell
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 Homo sapiens
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