Literature summary for 2.7.7.84 extracted from

Paeri, M.; Kuusksalu, A.; Lopp, A.; Kjaer, K.H.; Justesen, J.; Kelve, M.
Enzymatically active 2,5-oligoadenylate synthetases are widely distributed among Metazoa, including protostome lineage (2014), Biochimie, 97, 200-209.

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Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
34700	-	x * 34700, calculated	Tedania ignis

Organism

Organism	UniProt	Comment	Textmining
Tedania ignis	U5XFV4	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2 ATP	-	Tedania ignis	pppA2'p5'A + diphosphate	synthesis of 2-5A dimer, trimer and tetramer with the prevalence of dimer among reaction products	?
3 ATP	-	Tedania ignis	pppA2'p5'A3'p5'A + 2 diphosphate	enzyme synthesizes triadenylates with the first linkage being a 2',5'-phosphodiester bond and the second one being a 3',5'-bond. The ratio of products containing 2',5'-linkage to the products with 3',5'-linkage is 2.4 in the presence of 100 mg/ml poly(I)poly(C)	?
additional information	enzyme polymerizes ATP into 2',5'-linked and 3'-5'-linked oligoadenylates in the presence of synthetic dsRNA poly(I)poly(C). The presence of dsRNA is required	Tedania ignis	?	-	?

Subunits

Subunits	Comment	Organism
?	x * 34700, calculated	Tedania ignis

Synonyms

Synonyms	Comment	Organism
OAS	-	Tedania ignis

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Release 2023.1 (January 2023)