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Literature summary for 2.7.7.84 extracted from
- 2',5'-Oligoadenylates and related 2',5'-oligonucleotide analogues. 1. Substrate specificity of the interferon-induced murine 2',5'-oligoadenylate synthetase and enzymatic synthesis of oligomers (1983), Biochemistry, 22, 2116-2126.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3 ATP | Mus musculus | - |
pppA2'p5'A2'p5'A + 2 diphosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| L-cell | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3 1,N6-ethenoadenosine | - |
Mus musculus | ? | - |
? | |
| 3 2-beta-D-ribofuranosylthiazole-4-carboxamide | - |
Mus musculus | ? | - |
? | |
| 3 2-chloroadenosine | - |
Mus musculus | ? | - |
? | |
| 3 3-ribosyladenine | - |
Mus musculus | ? | - |
? | |
| 3 8-azaadenosine | - |
Mus musculus | ? | - |
? | |
| 3 8-bromoadenosine | - |
Mus musculus | ? | - |
? | |
| 3 adenosine | - |
Mus musculus | ? | - |
? | |
| 3 adenosine 1-oxide | - |
Mus musculus | ? | - |
? | |
| 3 ATP | - |
Mus musculus | pppA2'p5'A2'p5'A + 2 diphosphate | - |
? | |
| 3 cytidine | - |
Mus musculus | ? | - |
? | |
| 3 formycin | - |
Mus musculus | ? | - |
? | |
| 3 guanosine | - |
Mus musculus | ? | - |
? | |
| 3 inosine | - |
Mus musculus | ? | - |
? | |
| 3 ribavirin | - |
Mus musculus | ? | - |
? | |
| 3 sangivamycin | - |
Mus musculus | ? | - |
? | |
| 3 toyocamycin | - |
Mus musculus | ? | - |
? | |
| 3 uridine | - |
Mus musculus | ? | - |
? | |
| additional information | substrate specificity and possible products, overview. Selected nucleoside 5'-triphosphates are converted to 2',5'-oligonucleotides with the following order of efficiency for the nucleoside: 8-azaadenosine > adenosine = 2-chloroadenosine > sangivamycin > toyocamycin > formycin > 3-ribosyladenine > ribavirin > tubercidin > adenosine 1-oxide > 2-beta-D-ribofuranosylthiazole-4-carboxamide > inosine = 1,N6-ethenoadenosine > guanosine > 8-bromoadenosine = uridine > cytidine. Adenosine 5'-(beta,gamma-imidotriphosphate) is no substrate | Mus musculus | ? | - |
? | |
| tubercidin | - |
Mus musculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 2',5'-oligoadenylate synthetase | - |
Mus musculus |
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