Organism | UniProt | Comment | Textmining |
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Pseudomonas aeruginosa | - |
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General Information | Comment | Organism |
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physiological function | the KH-S1 domains of PNPase are required for the type III secretion system (T3SS) and bacterial virulence. PNPase shows a pleiotropic role in gene regulation. The RNA level of exsA is decreased in a mutant lacking the KH-S1 domains. The pilus biosynthesis genes are down regulated and the type VI secretion system (T6SS) genes are up regulated in the mutant, which is caused by increased levels of small RNAs, RsmY, and RsmZ. Deletion of the KH-S1 domains does not affect the transcription of RsmY/Z, but increases their stabilities | Pseudomonas aeruginosa |