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Literature summary for 2.7.7.8 extracted from

  • Haddad, N.; Tresse, O.; Rivoal, K.; Chevret, D.; Nonglaton, Q.; Burns, C.M.; Prevost, H.; Cappelier, J.M.
    Polynucleotide phosphorylase has an impact on cell biology of Campylobacter jejuni (2012), Front. Cell. Infect. Microbiol., 2, 30.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.8

Protein Variants

Protein Variants Comment Organism
additional information construction of a pnp inactivation mutant, comparative proteomic analysis and 81-176 phenotype, overview. Levels of peb3 and katA mRNA are significantly decreased in the pnp mutant strain compared to the parental strain, while gene expression of luxS and hsp90 remains unaffected by the pnp mutation, but not protein expression, overview. Poly(A) degradation by lysates of the pnp mutant strain is almost totally non-responsive to phosphate addition Campylobacter jejuni

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Campylobacter jejuni 5737
-

Organism

Organism UniProt Comment Textmining
Campylobacter jejuni
-
 strains 81-176 and F38011
-

Synonyms

Synonyms Comment Organism
PNPase
-
 Campylobacter jejuni
polynucleotide phosphorylase
-
 Campylobacter jejuni

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Campylobacter jejuni

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 assay at Campylobacter jejuni

General Information

General Information Comment Organism
malfunction the inactivation of the pnp gene reduces significantly the ability of Campylobacter jejuni to adhere and to invade Ht-29 cells, the mutant strain exhibits a decrease in swimming ability and chick colonization, 81-176 phenotype, overview. The pnp mutation do not induce profound proteomic changes suggesting that other ribonucleases in the organism might ensure this biological function in the absence of PNPase Campylobacter jejuni
physiological function the role of PNPase is pleiotropic Campylobacter jejuni