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Literature summary for 2.7.7.7 extracted from
- DNA polymerase I from Escherichia coli (1974), Methods Enzymol., 29, 3-12.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | - |
Escherichia coli |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 109000 | - |
pol I | Escherichia coli |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| deoxynucleoside triphosphate + DNAn | Escherichia coli | - |
diphosphate + DNAn+1 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
pol I | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| polymerase I | Escherichia coli |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| deoxynucleoside triphosphate + DNAn | - |
Escherichia coli | diphosphate + DNAn+1 | - |
? | |
| deoxynucleoside triphosphate + DNAn | exonuclease 3'--5' activity, pol I | Escherichia coli | diphosphate + DNAn+1 | - |
? | |
| deoxynucleoside triphosphate + DNAn | exonuclease 5'--3' activity, pol I | Escherichia coli | diphosphate + DNAn+1 | - |
? | |
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