Application | Comment | Organism |
---|---|---|
drug development | due to the absence of the pathway in mammals enzyme provides a potential target for new antibiotics | Escherichia coli |
Crystallization (Comment) | Organism |
---|---|
vapor diffusion method | Escherichia coli |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
25700 | - |
2 * 25700, crystal structure analysis | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + 2-C-methyl-D-erythritol 4-phosphate | Escherichia coli | essential enzyme in the mevalonate-independent pathway of isoprenoid biosynthesis | diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + 2-C-methyl-D-erythritol 4-phosphate | - |
Escherichia coli | diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol | - |
? | |
CTP + 2-C-methyl-D-erythritol 4-phosphate | essential enzyme in the mevalonate-independent pathway of isoprenoid biosynthesis | Escherichia coli | diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 25700, crystal structure analysis | Escherichia coli |