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Literature summary for 2.7.7.6 extracted from
- Structures of bacterial RNA polymerase complexes reveal the mechanism of DNA loading and transcription initiation (2018), Mol. Cell, 70, 1111-1120 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | P0A8T7 AND P0A8V2 AND P0A7Z4 AND P0A800 | P0A8T7: rpoC, DNA-directed RNA polymerase subunit beta, P0A8V2: rpoB, DNA-directed RNA polymerase subunit beta, P0A7Z4: rpoA, DNA-directed RNA polymerase subunit alpha, P0A800: rpoZ, DNA-directed RNA polymerase subunit omega | - |
| Escherichia coli K12 | P0A8T7 AND P0A8V2 AND P0A7Z4 AND P0A800 | P0A8T7: rpoC, DNA-directed RNA polymerase subunit beta, P0A8V2: rpoB, DNA-directed RNA polymerase subunit beta, P0A7Z4: rpoA, DNA-directed RNA polymerase subunit alpha, P0A800: rpoZ, DNA-directed RNA polymerase subunit omega | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| RNAP | - |
Escherichia coli |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | gene transcription is carried out by multi-subunit RNA polymerase. Transcription initiation is a dynamic multi-step process that involves the opening of the double-stranded DNA to form a transcription bubble and delivery of the template strand deep into the RNAP for RNA synthesis. Transcription bubble is stabilized by a helix separating the two DNA strands | Escherichia coli |
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Release 2023.1 (January 2023)
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