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Literature summary for 2.7.7.56 extracted from

  • Sulthana, S.; Quesada, E.; Deutscher, M.P.
    RNase II regulates RNase PH and is essential for cell survival during starvation and stationary phase (2017), RNA, 23, 1456-1464 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Escherichia coli P0CG19
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General Information

General Information Comment Organism
physiological function during ribosome degradation in starving cells, RNase II regulates the amount of RNase PH present, via RNase PH stability. RNase PH normally decreases as much as 90% during starvation, in the absence of RNase II the amount of RNase PH remains relatively unchanged. In the presence of RNase II, nutrient deprivation leads to a dramatic reduction in the amount of RNase PH, thereby limiting the extent of rRNA degradation and ensuring cell survival. In the absence of RNase II, RNase PH levels remain high, leading to excessive ribosome loss and ultimately to cell death Escherichia coli