Localization | Comment | Organism | GeneOntology No. | Textmining |
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Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P0CG19 | naturally acquired truncated inactive ribonuclease PH variant | - |
Synonyms | Comment | Organism |
---|---|---|
Rph-1 | - |
Escherichia coli |
General Information | Comment | Organism |
---|---|---|
physiological function | laboratory strains MG1655 and W3110 have naturally acquired the Rph-1 allele, encoding a truncated catalytically inactive RNase PH protein. Rph-1 protein inhibits RNase P-mediated 5'-end maturation of primary pre-tRNAs with leaders of less than 5 nucleotides in the absence of RppH, an RNA diphosphohydrolase. RppH is not required for 5'-end maturation of endonucleolytically generated pre-tRNAs in the Rph-1 strain and for any tRNAs in Rph mutant or Rp+x03 strains | Escherichia coli |