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Literature summary for 2.7.7.50 extracted from

  • Ogino, M.; Ito, N.; Sugiyama, M.; Ogino, T.
    The rabies virus L protein catalyzes mRNA capping with GDP polyribonucleotidyltransferase activity (2016), Viruses, 8, 144 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.50

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Sf21 insect cells Lyssavirus rabies

Organism

Organism UniProt Comment Textmining
Lyssavirus rabies
-
-
-
Lyssavirus rabies RC-HL
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA agarose column chromatography Lyssavirus rabies

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + (5')pp(5')-AACA(C/U)-mRNA the 5'-AAC sequence in the substrate RNAs is strictly essential for RNA capping with the L protein Lyssavirus rabies diphosphate + G(5')ppp(5')-AACA(C/U)-mRNA
-
 ?
GTP + (5')pp(5')-AACA(C/U)-mRNA the 5'-AAC sequence in the substrate RNAs is strictly essential for RNA capping with the L protein Lyssavirus rabies RC-HL diphosphate + G(5')ppp(5')-AACA(C/U)-mRNA
-
 ?

Synonyms

Synonyms Comment Organism
GDP polyribonucleotidyltransferase
-
 Lyssavirus rabies
L protein harbors guanosine 5'-triphosphatase and GDP polyribonucleotidyltransferase activities Lyssavirus rabies
PRNTase
-
 Lyssavirus rabies

General Information

General Information Comment Organism
metabolism the enzyme is essential for viral mRNA cap formation Lyssavirus rabies