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Literature summary for 2.7.7.50 extracted from

  • Takizawa, N.; Fujiwara, T.; Yamasaki, M.; Saito, A.; Fukao, A.; Nomoto, A.; Mizumoto, K.
    The essential role for the RNA triphosphatase Cet1p in nuclear import of the mRNA capping enzyme Cet1p-Ceg1p complex of Saccharomyces cerevisiae (2013), PLoS ONE, 8, e78000.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus the interaction of Ceg1 with RNA trisphophatase Cet1 essential for the nuclear localization of the Cet1-Ceg1 complex Saccharomyces cerevisiae 5634
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Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae Q01159 mRNA-capping enzyme subunit alpha
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Saccharomyces cerevisiae ATCC 204508 Q01159 mRNA-capping enzyme subunit alpha
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Synonyms

Synonyms Comment Organism
Ceg1
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Saccharomyces cerevisiae

General Information

General Information Comment Organism
physiological function RNA triphosphatase Cet1 and the RNA guanylyltransferase Ceg1 interact to form a mRNA capping enzyme complex. The guanylyltransferase activity of Ceg1 is stimulated by binding with Cet1. RNA trisphosphatase Cet1 is responsible for transport of Ceg1 into the nucleus, while triphosphatase activity of Cet1 is not required. The Cet1 223-549 region is sufficient for nuclear localization of Cet1 Saccharomyces cerevisiae