Literature summary for 2.7.7.49 extracted from

Bauman, J.D.; Patel, D.; Dharia, C.; Fromer, M.W.; Ahmed, S.; Frenkel, Y.; Vijayan, R.S.; Eck, J.T.; Ho, W.C.; Das, K.; Shatkin, A.J.; Arnold, E.
Detecting allosteric sites of HIV-1 reverse transcriptase by X-ray crystallographic fragment screening (2013), J. Med. Chem., 56, 2738-2746.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
fragment screening by X-ray crystallography revealed seven new inbhibitor binding sites within HIV-1 reverse transcriptase, of which three sites, i.e. the Knuckles, the NNRTI Adjacent, and the Incoming Nucleotide Binding sites are inhibitory in an enzymatic assay	Human immunodeficiency virus type 1 BH10

Organism

Organism	UniProt	Comment	Textmining
Human immunodeficiency virus type 1 BH10	P03366	-	-

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Release 2023.1 (January 2023)