Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Human Immunodeficiency Virus | reverse transcriptase supports RNA-directed DNA synthesis, DNA-directed DNA synthesis and DNA-directed RNA hydrolysis, the enzyme adopts opposite binding orientations on duplexes containing DNA or RNA primers, directing DNA synthesis or RNA hydrolysis activity respectively, binding orientation determines enzymatic activity of reverse transcriptase | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Human Immunodeficiency Virus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
deoxynucleoside triphosphate + DNAn | - |
Human Immunodeficiency Virus | diphosphate + DNAn+1 | - |
? | |
additional information | reverse transcriptase supports RNA-directed DNA synthesis, DNA-directed DNA synthesis and DNA-directed RNA hydrolysis, the enzyme adopts opposite binding orientations on duplexes containing DNA or RNA primers, directing DNA synthesis or RNA hydrolysis activity respectively, binding orientation determines enzymatic activity of reverse transcriptase | Human Immunodeficiency Virus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterodimer | heterodimer consisting of a p51 and a p66 subunit, the latter of which contains catalytically active DNA polymerase and RNAseH domains | Human Immunodeficiency Virus |
Synonyms | Comment | Organism |
---|---|---|
reverse transcriptase | - |
Human Immunodeficiency Virus |