Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | reverse transcription of poly(rA) in the presence of 3.5 mM ATP, initial velocity smoothly decreases between 3 and 7 mM MgCl2 and sharply drops below 3 mM. Addition of 3.5 mM ATP shifts the optimal MgCl2 concentration from 1 to 3 mM. At low Mg2+ concentration, reverse transcription of a natural template strongly increases despite a dramatically reduced intrinsic polymerase activity under such conditions. Low Mg2+ concentrations affect the RNA stability and indirectly decreased its degradation by the RNase H activity | Human immunodeficiency virus 1 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Human immunodeficiency virus 1 | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
HIV-1 RT | - |
Human immunodeficiency virus 1 |