Activating Compound | Comment | Organism | Structure |
---|---|---|---|
borano-3TCTP | alpha-Boranophosphate nucleoside analogs enhance 38fold the binding of Mg2+ ions to the active site of the enzyme-DNA-dNTP complex and alleviate the requirement of critical amino acids involved in phosphodiester bond formation | Human immunodeficiency virus 1 | |
borano-dTTP | 100fold decrease in polymerase activity caused by the R72A substitution is restored to wild-type levels using borano-dTTP. alpha-Boranophosphate nucleoside analogs enhance 38fold the binding of Mg2+ ions to the active site of the enzyme-DNA-dNTP complex and alleviate the requirement of critical amino acids involved in phosphodiester bond formation | Human immunodeficiency virus 1 |
Organism | UniProt | Comment | Textmining |
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Human immunodeficiency virus 1 | - |
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