Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.7.48 extracted from

  • Hunter, L.J.; Brockington, S.F.; Murphy, A.M.; Pate, A.E.; Gruden, K.; MacFarlane, S.A.; Palukaitis, P.; Carr, J.P.
    RNA-dependent RNA polymerase 1 in potato (Solanum tuberosum) and its relationship to other plant RNA-dependent RNA polymerases (2016), Sci. Rep., 6, 23082.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.48

Cloned(Commentary)

Cloned (Comment) Organism
gene StRDR1, phylogenetic analysis, enzyme expression analysis by quantitative reverse transcriptase PCR Solanum tuberosum

Protein Variants

Protein Variants Comment Organism
additional information silencing of the transcripts of StRDR1a and StRDR1b by dsRNA hairpin transcripts, expression of silencing constructs for StRDR1 does not affect the expression of the StRDR2 or the StRDR6 genes. Gene silencing does not affect the plant susceptibility to plant viruses, potato virus Y, potato virus X, and tobacco mosaic virus Solanum tuberosum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nucleoside triphosphate + RNAn Solanum tuberosum
-
 diphosphate + RNAn+1
-
 ?

Organism

Organism UniProt Comment Textmining
Solanum tuberosum M1C692 cv. Pentland Dell, gene StRDR1 or PGSC0003DMG400023601
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nucleoside triphosphate + RNAn
-
 Solanum tuberosum diphosphate + RNAn+1
-
 ?

Synonyms

Synonyms Comment Organism
RDR
-
 Solanum tuberosum
RNA-dependent RNA polymerase 1
-
 Solanum tuberosum

Expression

Organism Comment Expression
Solanum tuberosum RDR1 expression is elevated following plant treatment with defensive phytohormones, StRDR1 is salicylic acid-responsive up

General Information

General Information Comment Organism
evolution the enzyme belongs to the RDR gene family, phylogenetic analysis of RDR genes present in potato and in a range of other plant species, overview Solanum tuberosum
malfunction StRDR1 transcript accumulation decreases in transgenic potato plants constitutively expressing a hairpin construct. These plants when challenged with three viruses, potato virus Y, potato virus X, and tobacco mosaic virus show no increase in the susceptibility of potato to these viruses. Suppression of StRDR1 gene expression does not increase in the susceptibility to the viruses Solanum tuberosum
physiological function cellular RNA-dependent RNA polymerases catalyze synthesis of double-stranded RNAs that can serve to initiate or amplify RNA silencing. Enzyme RDR1 contributes to basal virus resistance in several plants Solanum tuberosum