Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,3-bis-(4-chloro-1H(3H)-triazolo[4,5-g]quinoline)propan-2-one | moderate antiproliferative activity for the cell lines tested | Bovine viral diarrhea virus 1 | |
3-benzyl-5-chloropyrido[3,2-g]quinoxalin-2(1H)-one | moderate antiproliferative activity for the cell lines tested | Bovine viral diarrhea virus 1 | |
4-chloro-2-(4-nitrophenyl)-3H-imidazo[4,5-g]quinoline | in addition, inhibitory to the recombinant hepacivirus enzyme. Compound shows no cytotoxicity for the various cell lines tested, exception made for HepG-2 cells | Bovine viral diarrhea virus 1 | |
4-chloro-2-(4-nitrophenyl)-3H-imidazo[4,5-g]quinoline | in addition, inhibitory to the recombinant bovine viral diarrhea virus enzyme. Compound shows no cytotoxicity for the various cell lines tested, exception made for HepG-2 cells | Hepacivirus C | |
5-chloro-3-phenylpyrido[3,2-g]quinoxalin-2(1H)-one | compound is equally cytotoxic for all cell lines tested | Bovine viral diarrhea virus 1 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bovine viral diarrhea virus 1 | - |
- |
- |
Hepacivirus C | - |
- |
- |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00006 | - |
pH 7.0, 22°C | Bovine viral diarrhea virus 1 | 4-chloro-2-(4-nitrophenyl)-3H-imidazo[4,5-g]quinoline | |
0.0004 | - |
pH 7.0, 22°C | Bovine viral diarrhea virus 1 | 1,3-bis-(4-chloro-1H(3H)-triazolo[4,5-g]quinoline)propan-2-one | |
0.0008 | - |
pH 7.0, 22°C | Hepacivirus C | 4-chloro-2-(4-nitrophenyl)-3H-imidazo[4,5-g]quinoline | |
0.001 | - |
pH 7.0, 22°C | Bovine viral diarrhea virus 1 | 5-chloro-3-phenylpyrido[3,2-g]quinoxalin-2(1H)-one | |
0.0012 | - |
pH 7.0, 22°C | Bovine viral diarrhea virus 1 | 3-benzyl-5-chloropyrido[3,2-g]quinoxalin-2(1H)-one |