Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | the enzyme requires either Mn2+ or Mg2+ for RNA-dependent RNA polymerase activity. NS5B undergoes conformational changes upon the binding of metal ions. This process does not significantly stimulate the binding to the RNA or NTP substrates | Hepacivirus C | |
Mn2+ | the enzyme requires either Mn2+ or Mg2+ for RNA-dependent RNA polymerase activity. NS5B undergoes conformational changes upon the binding of metal ions. This process does not significantly stimulate the binding to the RNA or NTP substrates | Hepacivirus C |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Hepacivirus C | P26663 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
nucleoside triphosphate + RNAn | - |
Hepacivirus C | diphosphate + RNAn+1 | - |
? |