KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.1 | - |
[L-glutamate:ammonia ligase (ADP-forming)] | pH 7.5, 22°C | Escherichia coli | |
3.9 | - |
ATP | pH 7.5, 22°C | Escherichia coli | |
3.9 | - |
ATP | ATP in form of MgATP2- | Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [L-glutamate:ammonia ligase (ADP-forming)] | Escherichia coli | inactivation of [L-glutamate:ammonia ligase (ADP-forming)] by attachment of the adenylyl moiety of ATP | diphosphate + [L-glutamate:ammonia ligase (ADP-forming)] -(AMP) | - |
r | |
ATP + [L-glutamate:ammonia ligase (ADP-forming)] | Escherichia coli B / ATCC 11303 | inactivation of [L-glutamate:ammonia ligase (ADP-forming)] by attachment of the adenylyl moiety of ATP | diphosphate + [L-glutamate:ammonia ligase (ADP-forming)] -(AMP) | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
B | - |
Escherichia coli B / ATCC 11303 | - |
B | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
ATP + [glutamine synthetase]-L-tyrosine = diphosphate + [glutamine synthetase]-O4-(5'-adenylyl)-L-tyrosine | mechanism | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [glutamine synthetase]-L-tyrosine | - |
Escherichia coli | diphosphate + [glutamine synthetase]-O4-(5'-adenylyl)-L-tyrosine | - |
? | |
ATP + [glutamine synthetase]-L-tyrosine | - |
Escherichia coli B / ATCC 11303 | diphosphate + [glutamine synthetase]-O4-(5'-adenylyl)-L-tyrosine | - |
? | |
ATP + [L-glutamate:ammonia ligase (ADP-forming)] | - |
Escherichia coli | diphosphate + [L-glutamate:ammonia ligase (ADP-forming)]-(AMP) | - |
r | |
ATP + [L-glutamate:ammonia ligase (ADP-forming)] | - |
Escherichia coli B / ATCC 11303 | diphosphate + [L-glutamate:ammonia ligase (ADP-forming)]-(AMP) | - |
r | |
ATP + [L-glutamate:ammonia ligase (ADP-forming)] | inactivation of [L-glutamate:ammonia ligase (ADP-forming)] by attachment of the adenylyl moiety of ATP | Escherichia coli | diphosphate + [L-glutamate:ammonia ligase (ADP-forming)] -(AMP) | - |
r | |
ATP + [L-glutamate:ammonia ligase (ADP-forming)] | inactivation of [L-glutamate:ammonia ligase (ADP-forming)] by attachment of the adenylyl moiety of ATP | Escherichia coli B / ATCC 11303 | diphosphate + [L-glutamate:ammonia ligase (ADP-forming)] -(AMP) | - |
r | |
additional information | enzyme also catalyzes a phosphate exchange between ATP and diphosphate, which is also stimulated by glutamine | Escherichia coli | ? | - |
? | |
additional information | enzyme also catalyzes a phosphate exchange between ATP and diphosphate, which is also stimulated by glutamine | Escherichia coli B / ATCC 11303 | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Escherichia coli |