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Literature summary for 2.7.7.41 extracted from
- CDP-DAG synthase 1 and 2 regulate lipid droplet growth through distinct mechanisms (2019), J. Biol. Chem., 294, 16740-16755 .
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CTP + phosphatidate | Homo sapiens | - |
diphosphate + CDP-diacylglycerol | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O95674 | - |
- |
| Homo sapiens | Q92903 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HEK-293T cell | - |
Homo sapiens | - |
| HeLa cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CTP + phosphatidate | - |
Homo sapiens | diphosphate + CDP-diacylglycerol | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CDP-DAG synthase | - |
Homo sapiens |
| CDS1 | isoform | Homo sapiens |
| CDS2 | isoform | Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | isoform CDS2 deficiency, but not isoform CDS1 deficiency, promotes the lipid droplet association of diacylglycerol-O-acyltransferase 2 and glycerol-3-phosphateacyltransferase 4 and impairs initial lipid droplet maturation | Homo sapiens |
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Release 2023.1 (January 2023)
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