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Literature summary for 2.7.7.41 extracted from

  • Blunsom, N.J.; Gomez-Espinosa, E.; Ashlin, T.G.; Cockcroft, S.
    Mitochondrial CDP-diacylglycerol synthase activity is due to the peripheral protein, TAMM41 and not due to the integral membrane protein, CDP-diacylglycerol synthase 1 (2018), Biochim. Biophys. Acta Mol. Cell Biol. Lipids, 1863, 284-298 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.41

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Rattus norvegicus 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CTP + phosphatidate Rattus norvegicus
-
 diphosphate + CDP-diacylglycerol
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus D3ZKT0
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
H9c2 cell
-
 Rattus norvegicus
-
heart
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CTP + phosphatidate
-
 Rattus norvegicus diphosphate + CDP-diacylglycerol
-
 ?

Subunits

Subunits Comment Organism
? x * 55000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
CDP diacylglycerol synthase
-
 Rattus norvegicus
TAMM41
-
 Rattus norvegicus

General Information

General Information Comment Organism
malfunction enzyme knockdown results in decreased mitochondrial CDP diacylglycerol synthase activity, decreased cardiolipin levels and a decrease in oxygen consumption Rattus norvegicus