Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dithiothreitol | activates | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
adenosine 5'-phosphosulfate | competitive with ATP and molybdate | Homo sapiens | |
ATP | - |
Homo sapiens | |
molybdate | - |
Homo sapiens | |
sulfate | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0048 | - |
adenylylsulfate | pH 8.0, 30°C | Homo sapiens | |
0.0346 | - |
diphosphate | pH 8.0, 30°C | Homo sapiens | |
0.1 | - |
ATP | pH 8.0, 30°C, reaction with molybdate | Homo sapiens | |
0.15 | - |
ATP | pH 8.0, 30°C, reaction with sulfate | Homo sapiens | |
0.16 | - |
sulfate | pH 8.0, 30°C | Homo sapiens | |
1.3 | - |
molybdate | pH 8.0, 30°C | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O43252 | recombinant | - |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.00012 | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + MoO42- | - |
Homo sapiens | AMP + adenylylmolybdate | - |
? | |
ATP + sulfate | - |
Homo sapiens | diphosphate + adenylylsulfate | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | native enzyme, a dimer with each 71 kDa subunit containing an adenosine triphosphate sulfurylase and an adenosine 5'-hosphosulfate kinase domain, catalyzes the overall formation of PAPS from ATP and inorganic sulfate | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
adenosine triphosphate sulfurylase | native enzyme, a dimer with each 71 kDa subunit containing an adenosine triphosphate sulfurylase and an adenosine 5'-hosphosulfate kinase domain, catalyzes the overall formation of PAPS from ATP and inorganic sulfate | Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000018 | - |
adenosine 5'-phosphosulfate | pH 8.0, 30°C | Homo sapiens | |
1 | - |
ATP | pH 8.0, 30°C, reaction with molybdate | Homo sapiens | |
1.1 | - |
ATP | pH 8.0, 30°C, reaction with sulfate | Homo sapiens | |
1.7 | - |
sulfate | pH 8.0, 30°C | Homo sapiens | |
14.3 | - |
molybdate | pH 8.0, 30°C | Homo sapiens |