Application | Comment | Organism |
---|---|---|
medicine | essential for the biosynthesis of lipopolysaccharides in gram-negative bacteria, potential target for the discovery of antibacterial agents | Escherichia coli |
Crystallization (Comment) | Organism |
---|---|
crystallized in space group P2(1), cell dimensions a = 46.1, b = 133.8, c = 48.5, beta 102.6° | Escherichia coli |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
27030 | - |
calculated from cDNA | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + 3-deoxy-D-manno-octulosonate | Escherichia coli | - |
diphosphate + CMP-3-deoxy-D-manno-octulosonate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Escherichia coli | P42216 | PDB: 1H7F, 3-dimensional structure of KDO-CT, in presence of CMP | - |
Escherichia coli | P42216 | PDB: 1H7T, 3-dimensional structure of KDO-CT, in presence of CMP-NeuAc | - |
Escherichia coli | P42216 | PDB: 1H7H, 3-dimensional structure of KDO-CT, in presence of CTP | - |
Escherichia coli | P42216 | PDB: 1H7G, 3-dimensional structure of KDO-CT, in presence of CDP | - |
Escherichia coli | P42216 | PDB:1H7E, 3-dimensional structure of KDO-CT, unligated form | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + 3-deoxy-D-manno-octulosonate | - |
Escherichia coli | diphosphate + CMP-3-deoxy-D-manno-octulosonate | - |
r |
Synonyms | Comment | Organism |
---|---|---|
CKS | - |
Escherichia coli |
K-CKS | CKS involved in capsule expression | Escherichia coli |
L-CKS | CKS involved in lipopolysaccharide biosynthesis | Escherichia coli |