Any feedback?
Literature summary for 2.7.7.31 extracted from
- Identification of functional domains in TdIF1 and its inhibitory mechanism for TdT activity (2007), Genes Cells, 12, 941-959.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| TdT interacting factor 1 | releases TdT in the presence of dsDNA to exhibit TdT activity | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| TdT interacting factor 1 | negatively regulates TdT activity, TdT interacting factor 1 binds to the Pol beta-like region in TdT and blocks TdT access to DNA ends | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| deoxynucleoside triphosphate + DNAn | - |
Homo sapiens | diphosphate + DNAn+1 | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TdT | - |
Homo sapiens |
| terminal deoxynucleotidyltransferase | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
