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Literature summary for 2.7.7.31 extracted from

  • Deibel, M.R.; Coleman, M.S.
    Biochemical properties of purified human terminal deoxynucleotidyltransferase (1980), J. Biol. Chem., 255, 4206-4212.
    View publication on PubMed
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KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Co2+ divalent metal required Homo sapiens
Co2+ in decreasing order of specificity: Mg2+, Zn2+, Co2+, Mn2+ Homo sapiens
Mg2+ divalent metal required Homo sapiens
Mg2+ in decreasing order of specificity: Mg2+, Zn2+, Co2+, Mn2+ Homo sapiens
Mn2+ divalent metal required Homo sapiens
Mn2+ in decreasing order of specificity: Mg2+, Zn2+, Co2+, Mn2+ Homo sapiens
Zn2+ divalent metal required Homo sapiens
Zn2+ in decreasing order of specificity: Mg2+, Zn2+, Co2+, Mn2+ Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Reaction

Reaction Comment Organism Reaction ID
a 2'-deoxyribonucleoside 5'-triphosphate + DNAn = diphosphate + DNAn+1 rapid equilibrium random mechanism Homo sapiens
a

Source Tissue

Source Tissue Comment Organism Textmining
leukemia cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxynucleoside triphosphate + DNAn primer required Homo sapiens diphosphate + DNAn+1
-
 ?
deoxynucleoside triphosphate + DNAn reaction is not template directed Homo sapiens diphosphate + DNAn+1
-
 ?